WebDiscovery Education’s flagship Science Techbook, part of a complete science program, offers courses for grades K-12. See how our Science Techbook helps to inspire students and support your school’s science … WebCanvas. Canvas is a robust LMS that helps teachers innovate and students succeed. Canvas streamlines all the digital tools and content that teachers and students love, for a simpler and more connected learning experience. Login here.
Discovery of Brain-Penetrant Glucosylceramide Synthase …
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WebAs glycosphingolipid biosynthesis starts from ceramide glycosylation by glucosylceramide synthase (GCS), inhibiting GCS in the brain is a promising strategy for neurological GD. … WebFeb 21, 2024 · Inhibition of glucosylceramide synthase (GCS) is a major therapeutic strategy for Gaucher’s disease and has been suggested as a potential target for treating Parkinson’s disease. Herein, we report the discovery of novel brain-penetrant GCS inhibitors. Assessment of the structure–activity relationship revealed a unique pharmacophore in … WebABOUT - Payne Township happy anniversary yard signs