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Digoxin interstage mortality

WebIn the digoxin group, there was a trend toward a decrease in the risk of death attributed to worsening heart failure (risk ratio, 0.88; 95 percent confidence interval, 0.77 to 1.01; P = 0.06 ... WebJan 11, 2016 · typical mortality rates of 15% to 20% occurring around the stage 1 palliation (S1P), and interstage mortality (IM) rates of 10% to 15% in survivors discharged to …

(PDF) Effect of Digoxin on Interstage Outcomes following Stage I ...

WebJan 26, 2016 · Interstage mortality for those not on digoxin was 12.3%, compared to 2.9% among those on digoxin, with an adjusted hazard ratio of 3.5 (95% CI, 1.1–11.7; … WebNov 16, 2012 · Interstage mortality for those not on digoxin was 12.3%, compared to 2.9% among those on digoxin, with an adjusted hazard ratio of 3.5 (95% CI, 1.1–11.7; P=0.04). The number needed to treat to ... bob 93.3 playlist https://aminolifeinc.com

Impact of Digoxin Use on Interstage Outcomes of Single Ventricle Heart ...

WebMay 4, 2024 · Conclusions This systematic review and meta-analysis suggests that digoxin significantly decreases interstage period mortality with a concurrent significant decrease in weight for age. The odds of arrhythmia or other complications are not significantly different with digoxin based on current data. Competing Interest Statement. The authors have ... WebFeb 23, 2024 · Digoxin use at the time of discharge was the preeminent protective feature against home interstage mortality both by univariate analysis and advanced ML. The protective effect of digoxin for interstage mortality, despite an unclear therapeutic mechanism, has been reported in several studies [ 9 , 17 , 32 ]. WebMar 1, 2024 · Background Infants born with single right ventricle congenital heart disease (SVCHD) physiology, such as hypoplastic left heart syndrome and variants, are at a high risk for death or transplant during the interstage (IS) defined as the period between Stage 1 surgery (aorto-pulmonary shunt with arch reconstruction) and Stage 2 surgery (superior … bob839us purchase for cash now phone number

Impact of Digoxin Use on Interstage Outcomes of Single …

Category:Association of Digoxin With Interstage Mortality: Results From …

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Digoxin interstage mortality

Association of Digoxin With Interstage Mortality: Results From …

WebInterstage mortality was 9.4%. Digoxin use was associated with lower risk of death (P =.03) on univariable analysis, however no single medication was an independent predictor on regression analysis. Change in weight-for-age z-score was studied as outcome of somatic growth with 36.3% patients showing a decrease during the interstage period. WebMar 18, 2024 · Digoxin is used for the treatment of heart failure in pediatric patients and acts by controlling numerous functions of the cardiovascular system. Digoxin use in single ventricle congenital heart disease may decrease interstage mortality. The study will be conducted in approximately 48 subjects at approximately 13 investigational centers.

Digoxin interstage mortality

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WebJan 13, 2016 · Interstage mortality for those not on digoxin was 12.3%, compared to 2.9% among those on digoxin, with an adjusted hazard ratio of 3.5 (95% CI, 1.1–11.7; P=0.04). The number needed to treat to prevent 1 death was 11 patients. There were no differences in complications between the 2 groups during the interstage period. WebDec 1, 2024 · The impact of digoxin on interstage mortality remains unproven. Abstract. The use of Digoxin has been associated with improved interstage survival following …

WebResearch Explained: Digoxin Use Is Associated With Reduced Interstage Mortality in Patients With No History of Arrhythmia After Stage I Palliation for Single Ventricle Heart Disease. Interstage mortality (IM) remains significant after stage 1 palliation (S1P) for single-ventricle heart disease (SVD), with many deaths sudden and unexpected. WebFeb 20, 1997 · Background: The role of cardiac glycosides in treating patients with chronic heart failure and normal sinus rhythm remains controversial. We studied the effect of …

WebJan 13, 2016 · Background: Mortality for infants with single ventricle congenital heart disease remains as high as 8% to 12% during the interstage period, the time between … WebQuality improvement efforts have focused on reducing interstage mortality for infants with hypoplastic left heart syndrome (HLHS). In 1/2016, two publications reported that use of digoxin was associated with reduced interstage mortality. The degree to which these findings have affected real world pr …

WebJan 11, 2016 · Interstage mortality by surgical site (n=50 centers). This figure shows interstage mortality (IM) among the 544 infants in the …

WebJan 1, 2016 · Digoxin use in infants with single ventricle congenital heart disease is associated with significantly reduced interstage mortality, and the number needed to treat to prevent 1 death was 11 patients. Background Mortality for infants with single ventricle congenital heart disease remains as high as 8% to 12% during the interstage period, the … climbing arborist bcWebSep 1, 2024 · The use of digoxin has been associated with significantly lower interstage mortality (ISM) following stage 1 palliation (S1P) of single ventricle heart disease. 1, 2 Two separate studies demonstrated this association near simultaneously using data from the National Pediatric Cardiology Quality Improvement Collaborative (NPC-QIC) registry … bob 90 day fianceWebNational Center for Biotechnology Information climbing arborist bootsWebJan 26, 2016 · Interstage mortality for those not on digoxin was 12.3%, compared to 2.9% among those on digoxin, with an adjusted hazard ratio of 3.5 (95% CI, 1.1–11.7; P=0.04). The number needed to treat to ... bob 94.9 i heart radioWebApr 11, 2024 · cardiac function , digoxin , echocardiogram , interstage mortality , interstage period , single-ventricle congenital heart disease Search for Similar Articles … bob 94.9 morning showclimbing arboristWebSerum digoxin concentration (SDC) data were infrequently considered, but available data suggested a greater association between increasing SDC and all-cause mortality. This … bob 93.7 fm hampton roads