Cisplatin long term effects

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August undefined, 2024

WebGeneral Cisplatin (Platinol) Side Effects Kidney problems (nephrotoxicity), especially in elderly patients. Nausea and vomiting, both acute (within first 24 hours) and delayed (two to five days after infusion) Diarrhea Low blood cell counts (myelotoxicity, acute leukemia) Hearing problems- ringing ears. WebJan 11, 2009 · I'm wondering what the long term effects of carboplatin could be? Carboplatin is a weaker analog of cisplatin. Carboplatin doesn't cross-link DNA as …

Long-term complications of chemotherapy for germ cell tumours

WebCisplatin has shown activity against osteosarcoma, transitional cell carcinoma, squamous cell carcinoma (SCC), melanoma, mesothelioma, carcinomatosis and germinal cell … WebApr 7, 2024 · Purpose To analyze the effect of cisplatin cycles on the clinical outcomes of patients with locally advanced cervical cancer (LACC) treated with concurrent chemoradiotherapy (CCRT). Methods This study included 749 patients with LACC treated with CCRT between January 2011 and December 2015. A receiver operating … list of nba top scorers

Carboplatin Side Effects: Common, Severe, Long Term - Drugs.com

WebApr 12, 2024 · The long-term prognosis for women with recurrent endometrial cancer is also poor. The combination of the chemotherapy drugs cisplatin and paclitaxel has long been the standard treatment for women with advanced or recurrent endometrial cancer. But treatment options for these two groups of patients have changed recently, largely … WebJan 26, 2024 · But cisplatin and other similar platinum-containing drugs can damage the cochlea, leaving 40%–80% of adults, and at least 50% of children, with significant … imec headquarters

Potential Cause of Cisplatin-Linked Hearing Loss Identified

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WebThese side effects can include: Hair loss Mouth sores Loss of appetite Nausea and vomiting Diarrhea Increased chance of infections (from having too few white blood cells) Easy bruising or bleeding (from having too few blood platelets) Fatigue (extreme tiredness, often from having too few red blood cells) WebJun 14, 2024 · Common long-term side effects of chemotherapy include early menopause and weight gain. Rare side effects include heart problems and leukemia. Learn about short-term effects of chemotherapy . Early menopause Some chemotherapy drugs can damage the ovaries and stop regular menstrual cycles (amenorrhea). imeche application trackerWebFeb 24, 2024 · Long Term Side Effects of Chemotherapy for Cancer. Heart Damage. Chemotherapy can cause cardiac effects early in treatment, but in some cases, the … imeche annual report

"Check with your doctor immediately if any of the following side effects occur while taking cisplatin: More common Black, tarry stools blood in urine or stools burning, numbness, tingling, or painful sensations change in frequency of urination or amount of urine cough or hoarseness difficulty in … See more Commonly reported side effectsof cisplatin include: bone marrow depression, nephrotoxicity, and ototoxicity. Continue reading for a … See more Some side effects of cisplatin may occur that usually do not need medical attention. These side effects may go away during treatment as your … See more Along with its needed effects, cisplatin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediatelyif any of … See more Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. … See more " - Cisplatin long term effects

Cisplatin long term effects

Long-Term Side Effects of Cancer Treatment Cancer.Net

WebSep 18, 2024 · NCBI Bookshelf WebCisplatin is a platinum-based chemotherapeutic that has long since been effective against a variety of solid-cancers, substantially improving the five-year survival rates for cancer patients. Its use has also historically been limited by its adverse drug reactions, or cisplatin-induced toxicities (CITs). Of these reactions, cisplatin-induced nephrotoxicity (CIN), …

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WebSep 15, 2024 · SIDE EFFECTS. Nephrotoxicity - Dose-related and cumulative renal insufficiency is the major dose-limiting toxicity of cis-platin.Renal toxicity has been noted … WebApr 21, 2024 · If you’re receiving carboplatin or cisplatin chemotherapy, talk to your doctor about the risks to your hearing. Heart problems Chemotherapy can lead to high blood …

WebNov 2, 2024 · Some long-term side effects have been linked to elevated platinum levels, such as: tingling or burning of extremities low sex hormones high cholesterol high blood … WebCommon side effects of cisplatin Risk of infection This treatment can reduce the number of white blood cells in your blood. These cells fight infection. If the number of white blood …

WebThese side effects happen in more than 10 in 100 people (more than 10%). You might have one or more of them. They include: Increased risk of infection Increased risk of getting an infection is due to a drop in white blood cells. Symptoms include a change in temperature, aching muscles, headaches, feeling cold and shivery and generally unwell. WebFeb 1, 2024 · Check with your doctor immediately if any of the following side effects occur: More common. Black, tarry stools blood in urine or stools burning, numbness, …

WebNov 1, 2024 · Significant risks for long-term toxicities associated with cisplatin and platinum-based regimens were reported. The cumulative dose of cisplatin and …

WebTherapeutic efficacy of cisplatin-based treatment of late stage urothelial carcinoma (UC) is limited by chemoresistance. To elucidate underlying mechanisms and to develop new approaches for overcoming resistance, we generated long-term cisplatin treated (LTT) UC cell lines, characterised their cisplatin response, and determined the expression of … imeche application examplesWebMay 20, 2024 · In two of these trials, researchers swapped out cisplatin—which has long been the standard chemotherapy for this cancer but can cause long-term side effects, … list of nbc soap operasWebNov 17, 2024 · blistering, peeling, or loosening of the skin cough or hoarseness dark urine diarrhea difficult breathing drowsiness joint or muscle pain loss of appetite lower back or side pain muscle tremors nausea or vomiting rapid, deep breathing red, irritated eyes red skin lesions, often with a purple center restlessness seizures stomach cramps imeche apprentice membershipWebCisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, as manifested by a decline in the glomerular filtration rate (GFR), can be dose limiting. imeche application workshopWebConclusions: Renal function before and after cisplatin treatment is an important determinant of long-term Pt exposure. Known long-term effects of testicular cancer treatment, such as paraesthesia, hypogonadism, hypercholesterolaemia and hypertension, are associated with long-term circulating Pt exposure. list of nba teams without a championshipWebNov 24, 2024 · bloating or swelling of the face, arms, hands, lower legs, or feet blood in the urine or stools blurred vision burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings chest pain chills cloudy urine confusion cough coughing up blood diarrhea difficult or labored breathing difficulty in moving list of nba teams 2021WebDec 31, 2024 · cough or hoarseness, accompanied by fever or chills fever or chills lower back or side pain, accompanied by fever or chills numbness or tingling in fingers or toes painful or difficult urination, accompanied by fever or chills pinpoint red spots on skin skin rash or itching unusual bleeding or bruising unusual tiredness or weakness Rare list of nbc affiliates