Cisplatin hyponatriämie
WebOnset of severe hyponatremia following cisplatin (CDDP) administration has been previously reported. However, the risk factors associated with hyponatremia still remain … Webmostly solid tumors had hyponatremia, and of these, 11% had moderate (sodium [Na] 120–129 mEq/L) to severe (Na , 120 mEq/L) hyponatremia (1). This is disproportionately higher than the hyponatremia prevalence rates of 15%–30% reported for general medicine admissions (2). In cancer patients with nonsolid tumors, rates of hyponatremia are less.
Cisplatin hyponatriämie
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WebHyponatremia was defined and graded using the Common Terminology Criteria for Adverse Events, version 4.0, as follows: a serum sodium concentration from lower limit of normal to 130 mEq/L, grade 1; … WebMay 22, 2012 · The development of hyponatremia during cisplatin therapy bears special mention. Cisplatin stimulates AVP secretion to cause SIADH, but it can also directly damage renal tubules to interfere with sodium …
WebHyponatremia is a rare complication associated with cisplatin. The mechanism by which it causes hyponatremia is thought to be due to either inducing SIADH or by renal salt wasting syndrome (RSWS) [1]. It is unclear why it occurs but it is believed that pharmacogenetics plays an essential role. WebJun 2, 2024 · Group A received cisplatin 60-100 mg/m 2 q 3 weeks with laboratories before day 1, group B received cisplatin 60-75 mg/m 2 q 3 weeks with laboratories before days 1 and 8 of each cycle and group C had weekly cisplatin 40 mg/m 2 and laboratories. Association between hypomagnesemia, hypokalemia, hyponatremia, and risk of AKI, as …
WebHyponatremia is one of the common electrolyte disorders associated with cisplatin (CDDP) administration. We report here two cases of hyponatremia associated with CDDP. Case 1 : A 75-year-old man with urothelial carcinoma of bladder (cT3N1M0) underwent neoadjuvant chemotherapy with CDDP and gemcitabi … Webdromes have distinct clinical characteristics and managements. The key differential diagnostic feature for RSWS is the excessive urinary excretion of sodium, whereas the urinary excretion of sodium in SIADH is normal or decreased. The treatment for RSWS is supplement of salt, which is opposite to the treatment of SIADH. We report a case of a …
WebCisplatin-induced hyponatremia and renal sodium wast-ing. Acta Oncol 1995;34:264-5. 12. Cao L, Joshi P, Sumoza D. Renal salt-wasting syndrome in a patient with cisplatin-induced hyponatremia. Am J
WebFeb 1, 1999 · Hypomagnesemia is a well known side-effect in patients receiving cisplatin-containing chemotherapy. Cisplatin induces hypomagnesemia through its renal toxicity possibly by a direct injury to mechanisms of magnesium reabsorption in the ascending limb of the loop of Henle as well as the distal tubule. cannot smooth on variables with nasWebwhich can induce hyponatremia. As regards platinum, cisplatin is more frequently described than carbopla-tin.[1] The incidence of hyponatremia secondary to cisplatin can be as high as 43%,[6] the mechanism of action by which cisplatin induces hyponatremia is 100 105 110 115 120 125 130 135 140 0 100 200 300 400 500 600 Na + urine (ml/H) … can not sleeping stunt growthWebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, as manifested by a decline in the glomerular filtration rate (GFR), can be dose … cannot slide out the dishwasherWebMar 1, 2024 · Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude of renal disorders including acute kidney injury with ... flag corpsWebJul 8, 2010 · Cisplatin based therapy for the treatment of solid organ tumors is commonly associated with several renal abnormalities including; *hypokalemia. * hypomagnesemia. … can not smoking make you depressedWebNational Center for Biotechnology Information cannot sleep through the nightWebElectrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management. Platinum chemotherapy, particularly cisplatin, is commonly associated … flag cords